Standard test method for water vapor transmission rate of plastic films and sheets using modulated infrared sensors The purpose of this test method is to obtain reliable values of WVTR for plastic films and sheets. WVTR is an important characteristic of packaging materials that is directly related to shelf life and stability of the packaged product. The data from this test method is suitable as a reference test method if the buyer and seller agree on sampling procedures, standardization procedures, test conditions and acceptance criteria. 1.1 This test method covers the procedures for determining the rate of water vapor passage through flexible barrier materials. The method applies to sheets and films up to 3 mm (0.1 in.) thick, consisting of single or multiple layers of synthetic or natural polymers and foils, including coated materials. It provides for the determination of ( 1 ) water vapor transmission rate (WVTR), ( 2 ) film permeability to water vapor, and ( 3 ) water vapor permeability coefficient for homogeneous materials. Note 1 - Water vapor permeability and water vapor permeability values must be used with caution. the inverse relationship between WVTR and thickness and the direct relationship between WVTR and water vapor partial pressure difference may not always be applicable. 1.2 This standard is not intended to address all safety issues, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory restrictions prior to use. GBPI's  Moisture Vapor Transmission Analyzer is used to test the water vapor transmission rate (WVTR) of films or sheet materials. It is suitable for testing the water vapor transmission performance of films, sheets, papers, packaging parts and many other materials in the fields of food, pharmaceuticals, medical devices, daily chemicals, photovoltaic electronics, etc. It is an ideal configuration instrument for off-line or on-line testing of the barrier performance of packaging materials by the majority of production units in the packaging industry. Testing principle W413 2.0 water vapor transmission rate tester adopts the principle of infrared method. The pre-treated specimen is fixed in the middle of the test chamber, and the test chamber is divided into high humidity side and low humidity side, compressed air flows on one side of the film, dry nitrogen (carrier gas) flows at a fixed speed on the other side, due to the existence of humidity gradient, water vapor will penetrate from the high humidity side to the low humidity side, the water vapor through the specimen is carried to the infrared sensor by the flow of dry nitrogen, and the water vapor transmission rate of the specimen is obtained by the electrical signal output from the sensor. Water vapor transmission rate of the specimen and other parameters. GBPI specializes in the production of package testing instruments, with many ...

In the production process of rubber, plastic and other products, in order to prolong the service life of the product and have good anti-oxidation, smoothness, flexibility and other properties, antioxidants, anti-blocking agents, plasticizers and other additives are often mixed. In addition to this, it is difficult to completely react the individual monomers used to prepare the product. Experiments have shown that these additives and residual monomers will slowly migrate outward in rubber, plastic and other products. When rubber and plastic products are in direct contact with food and medicine in packaging or other forms, these substances are likely to migrate. In food and medicine, food safety incidents such as "liquor plasticizer incident" and "toxic plastic wrap incident" are all related to the migration of harmful substances in packaging. Monitoring of Migratory Substances in Articles. Pacifiers are mostly used by infants and are in direct contact with the milk powder and oral cavity. The functional development of various organs of infants is not perfect. There are more migratory substances in the pacifier, which is more harmful to the baby. The total amount of control to ensure the safety of infant food intake. Each country has national standards, such as Thailand Thailand mandates TIS 1025-2562 (2019) as a new standard for pacifiers. This will take effect on December 13, 2021. On June 16, 2021, the Ministry of Industry of Thailand published a regulation in the Government Gazette requiring TIS 1025-2562 (2019) as a standard for pacifiers (the regulation). This industry standard is mainly based on EN 1400:2013+A1:2014 and contains requirements related to the materials, construction, performance, packaging and product information of such products. It is built with reference to information from the manufacturer, the user and the following documents: EN 1400:2013+A1:2014 "Children's use and care articles - Pacifiers for infants and young children - Safety requirements and test methods" EN 71-3:2013+A2:2017 'Safety of toys - Part 3 "Migration of certain elements" EN 12868:2017 'Children's use and care articles - Method for determination of the release of N-nitrosamines and N-nitroso substances from elastomer or rubber teats and pacifiers DIN 53160-1:2010 "Determination of colour fastness of commonly used articles - Part 1: Artificial saliva test" ISO 105-A03:1993 'Textiles - Tests for colour fastness - Part A03: Grey scales for assessing dyeing' Ministry of Health Circular (No. 369) BE 2558 (2015) Re: Bottles and Containers for Infants and Young Children. TIS 1025-2562 (2019) also requires certain nipple materials/components to comply with certain chemicals/tests involving: Migration of 17 elements Release of N-nitrosamines and N-nitroso species 2-mercaptobenzothiazole release Antioxidant release formaldehyde release Bisphenol A (BPA) release Color fastness Volatile compound content Test methods and instruments The AUTO ZF3600 total migration and ...

I. Overview A packaging system is the sum of all packaging components that contain and protect a pharmaceutical product, including packaging components that come into direct contact with the drug and secondary packaging components. This technical guide is mainly applicable to the packaging system of chemical injection. The packaging system for injectables should be able to maintain the integrity of the product contents while preventing microbial invasion. Package integrity, also known as container-closure integrity, refers to the ability of the packaging system to prevent the loss of contents, microbial invasion, and the entry of gases (oxygen, air, water vapor, etc.) or other substances to ensure that the drug continues to meet safety and quality requirements. package integrity test , or container-closure integrity test, CCIT, is a package leak test (including physicochemical or microbiological testing methods) that detects any rupture or seam, some of which can determine the size and/or location of the leak. This technical guide is drafted with reference to relevant domestic and international technical guidelines and standards, focusing on the selection and validation of sealing inspection methods for injectable packaging systems, with the aim of facilitating the research and evaluation of chemical injectables at this stage. The drafting of this technical guide is based on the current knowledge of the issue, and will be revised and improved with the continuous improvement of relevant regulations and the improvement of technical requirements of drug research. II. General considerations The main types of leaks in injection packaging systems include: 1) microbial intrusion; 2) drug escape or external liquid/solid intrusion; and 3) change in headspace volume content, e.g., headspace inert gas loss, vacuum disruption, and/or external gas entry. The sealing quality requirements of the injection packaging system can be divided into: 1) the need to maintain sterility and product component content, without maintaining the headspace volume; 2) the need to maintain sterility, product component content and headspace volume; 3) the requirement to maintain sterility of multi-dose packaging, that is, after the package is opened, to prevent microbial invasion and leakage of drugs during use. Research related to the sealing of the injection packaging system should be carried out according to the product characteristics. Injectable packaging system sealability meets the requirements, which usually means that the packaging system has passed or can pass the microbial challenge test. A broad sense means that there are no leaks that would affect the quality of the drug product. Based on scientific studies and risk assessment, the maximum allowable leakage limits should be determined taking into account the packaging composition and assembly, the product contents, and the environment to which the product may be exposed during its life cycle. A packaging system is con...

1, flexible packaging product market characteristics 2, the type and form of flexible packaging structure 3, the common testing methods and testing tools 4, the shallow media volume control process of several methods 5, the construction of the packaging laboratory points 1.flexible packaging products market characteristics 1.1, the development of flexible packaging is becoming more and more mature, rapid development, small-scale, many manufacturers, accounting for the proportion of national economic output value is rising. 2.1, packaging to the development of specialization instead of scale development, aggregation about the development of higher costs, service industry characteristics: small orders, many varieties, short delivery period, suitable for specialization. 3.1, the deep processing of agricultural and sideline products is a huge market, such as vegetables, fruit, grain, meat and poultry, eggs, in developed countries there are few farmers' markets. Farmers' markets are gradually replaced by supermarkets, and free market meat cases have evolved from frozen sales to the popular fresh sales. Fresh packaging presents a huge business opportunity for many packaging companies, which has achieved the blow molding market. In Japan today, cooking at home is a grand affair, mostly fast food, providing a market for many Chinese high-barrier film manufacturers. The accelerated pace of life, the traditional way of life is rapidly impacted, life towards convenience, clean food, fast food is the inevitable trend of development, all goods are quantitatively packaged, the development of China's packaging industry for tomorrow points the way, packaging will always be vigorous. 2.the type and form of flexible packaging structure     Today's world is short of natural resources, from the saving of resources and protection of the environment, high consumption of wood, iron, glass and other hard packaging is gradually replaced by flexible packaging, flexible packaging multi-layer composite structure and multi-layer co-extruded film provides a wide range of protective properties. Structure Performance Application NYCON/TIE/PE High strength, better barrier properties Weight packaging, liquid packaging, electronic light industry product packaging PE/TIE/NYLON/TIE/PE High strength, better barrier properties Weight packaging, milk powder, electronic light industrial product packaging PE/NYLON/PE/NYLON/PE/EVOH/PE High strength, high barrier Toothpaste tubes, preserved food, pharmaceutical packaging     The quality and technical requirements of different types of packaging films and morphological structures are very different, for example, the quality difference between cast film and blown film.     In blown film, the elongation rate is lower than that of cast film due to the process, and in blister packaging, there is a certain requirement for elongation rate, so cast film is usually used. We have customers in Zhongshan and Dongguang who...

On March 10, 2022, Shan Lipo, director of the Small and Medium Enterprise Development Promotion Center of the Ministry of Industry and Information Technology, led the team, Zhao Yi, deputy director of the Industry Promotion Center (Guangzhou) of the Small and Medium Enterprise Development Promotion Center of the Ministry of Industry and Information Technology, Cheng Yougen, deputy director of the Guangdong Provincial Bureau of Small and Medium Enterprises, Guangzhou Industry and Information Technology Co., Ltd. Ye Huadong, Director of the Small and Medium Enterprise Bureau of the Information Technology Bureau, Guo Xiong, Director of the Private Economy Division of the Guangzhou Bureau of Industry and Information Technology, Director of the Small and Medium Enterprise Department of the Guangzhou Bureau of Industry and Information Technology, Yi Huaiyu, Deputy Director of the Huangpu District Bureau of Industry and Information Technology, Huangpu Tan Jianwei, Director of the Small and Medium Enterprise Department of the District Bureau of Industry and Information Technology, and other leaders visited Guangzhou Biaoji Packaging Equipment Co., Ltd., Zhou Xuecheng, Chairman of GBPI, Zhou Xuehui, General Manager of GBPI, and company executives warmly welcomed and accompanied them throughout the process. Shan director and his party first came to the laboratory and production workshop of barrier performance testing instruments on the second floor, visited the production workshop and laboratory of water vapor transmission rate tester, gas transmission rate tester and oxygen transmission rate tester, and observed the live demonstration of IOT interoperability of products, which were highly evaluated by leaders at all levels. After that, the delegation visited the production workshop and digital laboratory of basic instruments. They learned about the components of the digital laboratory system in detail, including: connection to ERP system, automatic generation and printing of QR code based on sample information, one-click entry of sample information by scanning QR code with a code gun, automatic collection of test data, support for data screening of the same batch number, one-click generation of test reports, laboratory management functions, remote expansion support, etc. During the seminar, Mr. Zhou reported the development history of GBPI, the advantages of its products and the difficulties faced by the company at present, and the experts and leaders spoke highly of the achievements of GBPI in the industry and its digital product innovation. On the spot, he suggested GBPI to declare the qualification of National Key Specialized and New Enterprise and provided the way to declare the qualification. Director Shan pointed out that the benign development of enterprises must establish good school-enterprise cooperation, formulate a talent training plan suitable for the development of enterprises, solve the problem of supplying talents for enterprises, and...