Full-Automatic Overall Migration Tester -AUTO ZF1200

Test principle

Put the solution to be tested into the solvent storage dish of the automatic feeding system. The evaporation cup in the test chamber is heated according to the set temperature, cooled, weighed, and the steps are repeated until the constant weight value is reached. Add the solution to be tested into the evaporating cup, heat and evaporate in a water bath, heat the cavity to 105°C for drying, and cool down. After the evaporating dish is cooled, use a balance (sensitivity: 0.01mg) to judge the constant weight, and the experiment is terminated if the constant weight requirement of the project is met. 

Standard

Purified water: "Purified water" in Part Two of "Chinese Pharmacopoeia" 2020 Edition, "European Pharmacopoeia" EP9.0 WATER, PURIFIED

Pharmaceutical packaging materials: non-volatile items in the dissolution test of "National Standards for Pharmaceutical Packaging Materials"

Food contact materials: GB 31604.8-2016, EN 1186-3:2002 method A, Standards and Specifications for Utensils, Containers and Packages of Korea Ministry of Health and Welfare chapter IV 2-8.

Cigarette tipping paper: YQ/T 59-2015

Chemical reagents: GB/T 9740-2008

Water quality testing: GB 8538-2016, DZT0064.9-2021, GBT 14415-2007, GBT5750.4-2006

Solid samples (drugs, etc.): "Chinese Pharmacopoeia" 2020 Edition Four "Extraction" and "Loss on Drying" items

"United States Pharmacopoeia" USP40-NF35<921> WATER DETERMINATION

Specification

Application

	Purified water	Applicable to the test of non-volatile content in purified water and sterile water for injection in the pharmaceutical industry.
	Drug packaging material	It is suitable for the test of non-volatile items in the dissolution test of plastic and rubber pharmaceutical packaging materials
	Food contact material	It is suitable for various food utensils, containers and food packaging films, cans or other food tools, pipes and other products made of polyethylene, polystyrene, polypropylene, perchlorethylene resin as raw materials in different food simulants Determination of total migration after immersion.
	Cigarette pack material	Applicable to the total migration test of the soaking liquid of cigarette tipping paper.
	Chemical reagent	Suitable for chemical reagents, such as ethanol, acetic acid, n-hexane, chloroform and other organic solvents with a boiling point below 100 °C for evaporation residue testing.
	Domestic water and drinking water, industrial water, sewage	It is suitable for the total dissolved solids test of domestic drinking water, drinking natural mineral water, ground water, drinking water, swimming pool water, urban sewage, industrial boiler water, etc.
	Solid samples, pharmaceutical particles	Applicable to solid samples, such as empty capsules, microcrystalline cellulose and other medicines, or other solid particles for loss on drying, dryness or moisture testing.

Features

 Cold and hot dual-chamber integrated control system, automatic upgrade

It has an integrated system design of water bath evaporation, drying, cooling, constant

weight, and reagent recovery, which can effectively avoid the influence of the external

environment on the experiment, and the test is automated, efficient, and precise.

The cavity has a built-in water bath, which can automatically detect the water level through

the liquid level sensor, automatically add water, replenish water and drain, and

automatically control the temperature of the water bath. Multiple safety designs ensure the

safe treatment of water temperature, water bath water and waste liquid discharge in an all

round way.

Temperature control: International advanced electromagnetic temperature control

technology is adopted to automatically control the temperature rise and fall, and the

temperature control accuracy is 0.5°C.

 High-precision imported balance, isolation protection design

A high-precision imported balance is built in the chamber, with high weighing efficiency, the

balance resolution reaches 0.01 mg, and the 2-round drying process can reach a

constant weight of 0.3 mg.

The balance is placed in a fixed and stable protective cover with a water circulation

compartment. When performing evaporation and drying steps, the balance is completely

isolated from the test chamber, and when performing weighing, the temperature and

humidity are stable. The weighing data is stable and reliable, with good repeatability.